Biology Second Year - Short Questions

Briefly describe the genetics of Sickle cell Aneamia?

Briefly describe the work of Erwin Chargaff.

Compare telocentric and acrocentric chromosomes. G11

Define “phosphodiester bond”. Give its significance in the molecule of DNA.

Define Anticodons.

Define chromosomal aberrations and give their consequences.

Define chromosomal aberrations. Give some examples

Define chromosomal non disjunction.

Define chromosomal theory of inheritance. L10

Define Codons.

Define Gene in Proper Wording?

Define Genetic Code.

Define Karyotype

Define Karyotype give its significance.

Define nucleosome. L12

Define phosphodiester bond. State its role in DNA.

Define Point mutation and give two examples.

Define sense and Antisense strand.

Define telomere. give its significance.

Define transcription and how it is initiated. L10

Define Transcription.

Define transformation and write its role. L08

Define transformation.

Define transformation. Who discovered it?

Define Transforming principle.

Differentiate between chromosomal aberrations and point mutation. L10 L13

Differentiate Between Heterchromatin and Euchromatin.

Differentiate between heterochromatin and euchromatin. G11

Differentiate between Leading and Lagging strand of DNA.

Differentiate between leading and lagging strands.

Differentiate between peptidyl site and aminoacyle site on initiation complex at the time of translation.

Differentiate between Primer and Promoter.

Differentiate between promoter and primer

Differentiate between sense and anti-sense strand.

Differentiate between transcription and translation. G10

Differentiate heterochromation and euchromatin

Discuss One Gene one polypeptide hypothesis.

Draw a labeled sketch of the work of Hershey and Chase.

Draw different shapes of chromosomes.

Draw shapes of different types of chromosomes.

Draw structural formulae of adenine and guanine.

Enlist different shapes of chromosomes. L12

Enlist enzymes of DNA replication.

Enlist non-sense codons and their functions. L12

Enlist the Enzymes involve in DNA replication and Transcription.

Give chromosome distribution in Ascaris incurve.

Give length of Okazaki fragments. L12

Give the structure of a Nucleosome. How many nucleotides are present in the DNA duplex, around a core of eight Histones proteins?

How did crick and his colleagues determine that how many nucleotides are used to specify each amino acids?

How do histones and DNA interact with each other in chromosomes? G10

How phosphodiester bond is formed?

Mention types of chromosomes with reference to centromere position. G12

Name the components of RNA polymerase and their functions.

Name the start and stop codons.

State One Gene one polypeptide hypothesis.

What are basic requirements for production of recombinant DNA?

What are chromosomes? Why is it necessary to possess all the chromosomes?

What are constituents of purines? L12

What are different types of chromosomes on the basis of position of centromere?

What are mutagenes?

What are mutagens?

What are mutagens? Give an example G10

What are mutations? Classify.

What are Okazaki fragments? L09

What are point mutations? Give one example.

What are template and coding strand of DNA?

What are the contributions of Erwin Chargaff?

What are the Okazaki fragments?

What are three major classes of RNA?

What do you mean by initiation complex in translation?

What do you mean by Karyotype? Give its significance.

What do you mean by proof reading in DNA replication? justify

What is central dogma of biology?

What is chromosomal aberration?

What is core enzyme?

What is difference between acrocentric and telocentric chromosomes?

What is function of amino acyle tRNA synthetase?

What is fundamental cause of Alkaptonuria. What is its indication?

What is lagging strand?

What is meant by semi conservative model of DNA replication?

What is minimal medium? Give example with refrence to neurospora.

What is nucleosome?

What is one gene – one polypeptide hypothesis? Who proposed it?

What is one gene-one enzyme hypothesis? How did it change to one gene-one polypeptide hypothesis?

What is phenylketonuria?

What is phosphodiester bond? G09

What is phosphodiester linkage? Draw its structure. L13

What is point mutation? Give example. L12

What is post transcriptional modification when RNA polymerase II has done the process?

What is promoter site and describe it in eukaryotes.

What is promoter?

What is promoter? Give one example.

What is relation between code, codon and anti-codon?

What is RNA primer? What role does it play in DNA replication? G09

What is semiconservative replication?

What is semi-conservative replication? L08 L09

What is significance of work of Erwin Chargaff?

What is the difference between Kinetochore and Centrosome?

What is the function of DNA ligase and DNA helicase?

What is the function of RNA polymerase in transcription?

What is the role of non sense codon in translation?

What is transcription bubble and how it is formed? G12

What is transcription bubble?

What is transformation? L11, G11

What modifications are required after replication in two DNA strands?

What was the contribution of Frederick Sanger?

Who provided experimental and conclusive evidence about DNA as heredity material?

Who was T.H. Morgan? What is importance of his work?

Why 7-methyl GTP is attached by 5 - 5 linkage?

Why beadle and tatum are famous for?

Why DNA polymerase 3 is called Dimer?

Why histones are positively charged? G09

Why the Erwin Chargaff famous for? G12

Write a note on phenylketonuria.

Write characteristics of DNA polymerase-III.

Write chromosome number in mosquito, honey bee frog and corn cells.

Write important features of DNA polymerase III.